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Defining and benchmarking open problems in single-cell analysis. Research Square Platform LLC.
This paper defines and benchmarks key open problems in single-cell analysis, providing a comprehensive overview of challenges and solutions in the field.
http://dx.doi.org/10.21203/rs.3.rs-4181617/v1
Abstract: With the growing number of single-cell analysis tools, benchmarks are increasingly important to guide analysis and method development. However, a lack of standardisation and extensibility in current benchmarks limits their usability, longevity, and relevance to the community. We present Open Problems, a living, extensible, community-guided benchmarking platform including 10 current single-cell tasks that we envision will raise standards for the selection, evaluation, and development of methods in single-cell analysis.
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